Our client sought to create actionable healthcare provider (HCP) target lists, guided by medical claims data analysis, to guide outreach in rare disease.
CRA approach:
- CRA’s medical affairs consultants created patient cohorts through combinations of symptomatic International Classification of Diseases (ICD) codes, procedure codes, and prescription failures in a rare disorder with no specific ICD code
- Generated multiple rounds of HCP target lists, beginning with the highest-potential HCPs (~500 HCPs) and broadening to ~3,000 HCPs
- Mapped out follow-up approach for HCPs, including outreach emails and scripts, profiling questionnaires, and key talking points around rare disease testing options
- Validated HCP target list with market research and physician profiling – approximately 25% of physicians either managed or suspected a patient of having the rare disease
Client impact:
- Patient and HCP cohorts were of approximately the same size as our client’s prior analysis, but CRA’s HCP target list had ~80% novel targets and 20% overlap with prior list
- Roll-up of HCP targets to Healthcare Organizations (HCOs) allowed for institution prioritization (greater HCP interest due to potential for larger number of patients)
- CRA outreach confirmed 10+ HCPs managing or suspecting 20+ patients with the rare disease
- Developed a searchable HCP database enabling the medical team to quickly identify the appropriate HCP for outreach depending on goal (e.g. setting up an advisory board, potential study discussions)
